Universal Organ Rescue Technology to Expand the Viable Donor Pool
Targa’s TBM-005 protects donor organs from ischemia-reperfusion injury, making more organs available for life-saving transplantation.
Rescue more organs.
Save more lives.
The organ rescue challenge
to the transplant list, each day
for an organ
Organ quality, not donor supply, limits transplantation.
After cessation of circulation, warm ischemia triggers cellular injury that continues during recovery, transport and reperfusion.
Donation after Cardiocirculatory Death (DCD) organs face high attrition due to warm ischemia, time-to-recovery constraints and quality concerns.
Current preservation and perfusion systems help evaluate organ function, but they do not actively mitigate ischemic injury that limits the use of DCD and other marginal organs.
Introducing
The organ-conditioning layer for the next generation of transplantation
Targa’s solution
TBM-005 is an ex vivo organ-conditioning additive for preservation and perfusion solutions
Unlike conventional preservation solutions that maintain organ status, TBM-005 actively targets the mechanism responsible for ischemia-reperfusion injury at the cellular level.
Device-agnostic and temperature-flexible, it integrates directly into existing workflows with no new equipment or procedural changes.
Applications
Expanding what’s possible in transplant and regenerative science
Accelerators and Support
